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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SEPT3 All Species: 16.97
Human Site: Y236 Identified Species: 31.11
UniProt: Q9UH03 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UH03 NP_061979.3 358 40704 Y236 E V N G I E F Y P Q K E F D E
Chimpanzee Pan troglodytes Q5R1W1 434 50272 K218 E I Q E H K I K I Y E F P E T
Rhesus Macaque Macaca mulatta XP_001102088 360 40906 Y238 E V N G I E F Y P Q K E F D E
Dog Lupus familis XP_857693 357 40495 F235 L E V N G I E F Y P Q K E F D
Cat Felis silvestris
Mouse Mus musculus Q9Z1S5 350 40019 Y236 E V N G I E F Y P Q K E F D E
Rat Rattus norvegicus Q9WU34 358 40579 Y236 E V N G I E F Y P Q K E F D E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505764 436 49083 V319 L L S N G I D V Y P Q K E F D
Chicken Gallus gallus Q5ZMH1 349 40206 D220 P D A D S D E D E E F K E Q T
Frog Xenopus laevis Q63ZQ1 352 40432 D220 P D A E S D E D E D F K E Q T
Zebra Danio Brachydanio rerio A2BGU8 361 40623 C247 L E V C G I E C Y P Q K E F D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P40797 539 60125 Y316 A Q H K I K I Y D F P A T L E
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_795119 662 73144 T555 L N K N T I E T Y P M K N L E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P25342 322 37006 T216 P Y D S E E L T D E E L E L N
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 38.2 98.8 99.1 N.A. 94.1 98.5 N.A. 54.8 43.2 43.8 77 N.A. 31.1 N.A. N.A. 34.1
Protein Similarity: 100 56.2 99.1 99.4 N.A. 94.9 99.1 N.A. 65.8 64.5 63.1 85.8 N.A. 45.2 N.A. N.A. 42.6
P-Site Identity: 100 6.6 100 0 N.A. 100 100 N.A. 0 0 0 0 N.A. 20 N.A. N.A. 6.6
P-Site Similarity: 100 33.3 100 26.6 N.A. 100 100 N.A. 33.3 20 13.3 20 N.A. 33.3 N.A. N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. 40.7 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 58.9 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 16 0 0 0 0 0 0 0 0 8 0 0 0 % A
% Cys: 0 0 0 8 0 0 0 8 0 0 0 0 0 0 0 % C
% Asp: 0 16 8 8 0 16 8 16 16 8 0 0 0 31 24 % D
% Glu: 39 16 0 16 8 39 39 0 16 16 16 31 47 8 47 % E
% Phe: 0 0 0 0 0 0 31 8 0 8 16 8 31 24 0 % F
% Gly: 0 0 0 31 24 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 8 0 8 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 8 0 0 39 31 16 0 8 0 0 0 0 0 0 % I
% Lys: 0 0 8 8 0 16 0 8 0 0 31 47 0 0 0 % K
% Leu: 31 8 0 0 0 0 8 0 0 0 0 8 0 24 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % M
% Asn: 0 8 31 24 0 0 0 0 0 0 0 0 8 0 8 % N
% Pro: 24 0 0 0 0 0 0 0 31 31 8 0 8 0 0 % P
% Gln: 0 8 8 0 0 0 0 0 0 31 24 0 0 16 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 8 8 16 0 0 0 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 8 0 0 16 0 0 0 0 8 0 24 % T
% Val: 0 31 16 0 0 0 0 8 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 8 0 0 0 0 0 39 31 8 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _